Besides providing bioinformatics services, our group of researchers and scientists work to train the next group who will be working in this pivotal area. In bioinformatics, we are bringing together biological, chemical, statistical, physical, computational, and other scientists to help improve the environment and create a situation where the world will be protected.
We are not only conducting research, but provide courses and seminars that combine bioinformatics with genomics and NGS data analysis. In this way, we are finding ways to improve the future for the next generations. This includes in such areas as:
Virtual Screening
Virtual screening uses algorithms and computer programs to determine sequencing or variations that could have an impact. This is a computational method that uses algorithms that have been developed by various research groups across the globe. This is a highly effective tool that continues to be upgraded as more information becomes available.
Drug Repurposing Services
One of the most important areas of research these days is the repurchasing of drugs. What has been discovered is that a medication prescribed or created for one ailment or malady can have great benefits for several different conditions. This drug repurchasing is an important research that is conducted at our lab, and instructors teach students how to find additional ways that a drug could have benefits beyond its original purpose.
Protein Modelling Services
Protein modeling services focuses on the amino acid sequence of the individual. We help to customize modeling services for the individual, helping to develop a complex set of proteins that is specific to the individual. We are able to use the genetic data to develop the protein structure for the individual, then translate the genetic sequence into the correct protein sequence.
Molecular Docking
Molecular docking has become a very important tool that is used in the development and discovery of new medications and drugs. Through the molecular docking method, we have been able to assist in the development and applications of several drugs. We have worked to create algorithms and scoring functions using software to help in the fight against diseases and other pathogens.
Molecular Dynamics
Molecular dynamics uses a computer simulation to determine how atoms and molecules will move. However, it can also be used in molecular biology to determine how complex systems can be analyzed. This is ideal in understanding sequences and the effects of pathogens and drugs on one another.
Target Identification
Target identification works to identify how a drug will work on a particular pathogen or disease. Through target validation, the benefits and challenges of using siRNA is evaluated against specific targets. Our research team is looking to conclude if a target pathogen is “druggable,” providing a therapeutic means by which the drug can successfully treat a condition.
Active Site Prediction
Active site prediction focuses on how a particular drug will effectively work against a pathogen or other disease. Using computational methods developed by our research team as well as researchers from across the globe, we are able to create simulated experiments to further understand how and if a drug will have therapeutic benefits.